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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2a6423a32b4b90c98f6f46aa5feffdd72e57bab6bfde743fe4ee58a83860f99' 
  AND token = 'n+EPjAb5PQxh96tjIWvqKX3pC9A6ugMQSnTbirRRgjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}