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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1612155d658d5b171eac401c68c270f9c72acfe122aa79693ce0cad38e0c75b' 
  AND token = 'tObGcg6fByXQxqf0eROIfg4NB/aKxSdeIQrLaHot2IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}