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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f21809f0adb14da2df450b34fffbd04a67890e15f2475a6bb2d6b8f25c360c' 
  AND token = 'EVxoBI5AsB60gJ1VDQvvAZIIwncUrDOnnSgkwL50YJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}