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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717b50a8f75ec5c23acb851d8364b6a535f5bf5f2c1c6d4c26540e7ccb05c71b' 
  AND token = 'NosEq14UcXqPgb6iIZPUNT7KN6Wxe5pH4OuB0q+c/8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}