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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779f5689d66624217fa4a6f8afbc7184fec085f19fd8d1686ca3df8df3ab5c86' 
  AND token = '/AKGp/q5mp7zema3VKWKSiSBmGrtWLv5vtHAELZ7pU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}