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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b391fb5072c04b58dfef34ad723acf963b2cc4168c9094bbef7427761f0f53d' 
  AND token = '1OUVVhdIKy+cEHCrZ/V4Cxv8IKrlT997Nv7aXFNru1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}