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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b942c10a9243027f080cdb220275d6ce3ba733416e93ff2e79cc24e928e017f5' 
  AND token = 'dDSZPSMSfW41dksqBGvLGwX+rAPiA7kcFv7E9b/DU4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}