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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725efc6e518d6725d90ba957a2b856d55a3839f1e0b40e62f37c7a49965d1020' 
  AND token = '8E+Y1NKnSEbJMRfpsLmiy/3q0CgdXxPSHsQltLMQMRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}