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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47dd66a4de6ea4ef07e90ca228bcd2997387d221d3a433e62049dab087099087' 
  AND token = '2Y87RkNsPvTBMYao+HngLn1V/MkqM0r5EvRpb/WMtS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}