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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19664fa0d019a022c8bc6344c758d6640a87fd41e69d58672f89782a3bb4bdc3' 
  AND token = 'ex/8X1+XFXUfdODzrt/VZL0owU96+LIQwa+070WysMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}