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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282549b9dae43656a30c9898942abccb75e83d478bf8e5bfba9dc268767a2c2f' 
  AND token = 'x9NlG0ejnTtN4m71z2W9ZpGFshOt9M3nJFI8IlWhhpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}