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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1ff11d98998bfa4a2df5668fadeb1c26ce0df5eb59021b2d91f43e827e4822' 
  AND token = '4Hb9MOUO/qkNNPhT9IzjiePpNjpq6Jt3gQvoLUShzpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}