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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32280b2fc14a75b34b4ccf3719b29e1df1a5d5e955c3f7086a3aefb6b02aa5d3' 
  AND token = 'ocU2Ib0ycjIzQgFYFmS9tbfU3Ypk6aXcyV289eZleuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}