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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1b3a53f1459059f684af48a75b3307c046e2031c7bd52f4d4e246d97708632' 
  AND token = 'LorkWKEjCJV0N8My0UcHKZkIyBPXanPYo2Ggv9WWyWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}