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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6104d9fb5e3fe9138b5b24131ca3af57b339087b90bfd7463eba912937b822f4' 
  AND token = 'RcJMFqXL80dhY8sy+/b2sBEEPFll2Laby08h9ZFF3vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}