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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a074dd113b971038df9879832eecc240c1b8cc4cbf27cfe64adb1e73996311' 
  AND token = '8pVL7RLefcZLmwzaEtRGmiicIAzmrUQII1wGKGS91CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}