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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef11b955787f8caca7dcd7639e1c734b30c00e6ac829c7cbece730da595df5a' 
  AND token = 'd3BPiqpLqeFEO695xwM+06+ubC/DfhAWGGjcplH4Tmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}