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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09e89f325561abd116e9666b7d1d5870ade3e3701922f1cf9f1bb52c7497ef9c' 
  AND token = 't2uruiAMLO/AOd/9drHnrOGb/WVDq3d0nItzA0fHHdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}