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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad492faf3bb8fbde3155fcf40759cd1a160bd5b833a4704b80e265efd15009a6' 
  AND token = 'AHniAJannx6G00F7uE5qItIKlgdFv+q+XoiOJKGV+Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}