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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '236987f533af9041529d729841a423ed31994719c4418bd166d1022df1256003' 
  AND token = 'Re6tFx1N8a/HiADSe+8i3ubzQEQXmKGCjMnV9Ejfuqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}