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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb02a6cf5693a658834d5cdc9a5e24757d334a0dd73d0e5bacab1a002f404a9' 
  AND token = 'sJeLRzO23H6JX7Ll6TlWFULpdv7hJVIS5qTIxCOT3hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}