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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c3b5e71ceead3533991be6151d9eb4e13a08b3aaa9a45ade32c539378f2416' 
  AND token = 'Y6Smy+AilFbkzbFt0E8yfTZxr7lyOQEkD4tytsXJOH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}