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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403d2957c5037106f2a4265bc5004810b3a61d18921bccb0e4e202ef728c5e92' 
  AND token = 'T3RLM8u7c6TiGGL71zT7Q4C3vkm7dIIFhxmBW7UMIEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}