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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c445afaffaa83536f7bd33e565d2395cf14628b537e2c4796645b2612f855d' 
  AND token = '3CMylDRn2lKKrdUdtKYNXTlQ3KpTLQr2xCJs1ZhnJtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}