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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2576be7c1bb521dbc1dabd28d5b01476afc0250c3c576e2494e0f8d96dea60d8' 
  AND token = '8dXzV9Bk1EVOzd6oUpvpW18IaV3XXMBwLgzk5KDW4XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}