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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '271fe7f0d42dd8309987621d4d791378103ab397c16abb5e62e3b68d477b64e0' 
  AND token = 't0Yf2IzypTidTUBlFqQ3rX/E/fBcMDNm80QUy4/dQCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}