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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61dedee33ea03c35b1bb5bd6eb582aba280f645fa99ac9347cac98bc29b3c5d5' 
  AND token = 'EOjOPQ8XzKnxv6Ql6ct5iBpc5arf2ElI+4nE+5UXzhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}