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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '352cc6d7bbd0bd7e5fab6b8633736fe8da2d9a02765e89ba8497029270e9f186' 
  AND token = '+BTXXvGyWu2kMh5QSDyw4+KkicIpBoLsU4x1pRI/MD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}