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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3305d38a1e316ab29bb398065cf6be5b87e5e2f5df786e73acb9f1065b7b1acb' 
  AND token = 'vVj5QAXTWqvRqbQMtetTwT+yGErJ/nPEPj4Itv8MhfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}