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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fdfa48fb2410cb607908f1893e4480dfc5f3bb304db1d9a08684cfaef26f098' 
  AND token = '17ViryVR3S+zmlQt8oBYoyUtOuOcR1cjIWB1U4z8z74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}