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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed57dd6739f07227f0e8c6f44b38c2ff22ffd45b2603d28ad3ab6c29ce74875' 
  AND token = 'DX1LnELqrj+iNQTh0SljazUHU08s4Nyc4KMx0vBhWk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}