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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ccf76bf824ea1615415b0b9326902df15a857c7f0036b584e3d2b7bdecd63f' 
  AND token = 'ga4VQKzSMg6NhmvtxWQzBMu8CnuCtyv18WBS8n3isC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}