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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492265fd21191add5fb3a3193b37317f1398cc63427f796a4be8b2a1dc772bec' 
  AND token = 'dh4Fua+75+zIEHBx8a0C6hzil7qNgZAdQkMCkPzzeSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}