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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a2fb5d65839fb965967993cb60dface38f3c087d6330517b989ef58b908b00' 
  AND token = 'UJ6rKuJyLj2rZcZFKHbTuUdNmuyyYFph/UuzACKt15Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}