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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44612f4bad940461433243b13c195170c197a3fb5f7a47f82f3f91432dd554b7' 
  AND token = 'wYkSvBoM5tpZTpGwUw3CK0cH423SG1gsRrgtkUxoLfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}