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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21cd65a542cf9e2e9c116b33b5199eb5cbc0e61d8d9b72ccf82e6251ccdc124' 
  AND token = 'BC5gKdou+1X9NfRWzIqvgsfISymU9bTlb+p3Zl/FHNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}