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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eae3d575f5cebc51939c5f6bbb6c0d551540ba744901708a9aa47766fe258e4d' 
  AND token = 'NDBxWl5gASTLKQMeG+kvCLdU3e6Ilxl8lHpVcslZYFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}