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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55f78d9a8999284c29362d8f5bf55701cfd065973ecf8e016d77de657a48dc71' 
  AND token = 'NS54WSuHkW2Zlh1EQFQ1x++xp7pL5bkAHr9Bnb7MJ8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}