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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443d38668773d00718b949dc8feb891e14ed54651a42c7c4f156a5e76cf6afed' 
  AND token = 'W8cpk/mIE4csb5fUm+5J0O5Jzvmk4f1ji9pwIxZsQHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}