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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3582e7ae34e3e51c990db32bf19c7d0dbe351dabde4240eafdc5f11cc15f1e20' 
  AND token = '++e/NTH1/VjNhJo26npcP1TUJz+YTAZFjaN44x+0JU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}