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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b990e2b8248296e11f67a4d1fe132d822fed45d39e1a18d6cec645b0a16efd7' 
  AND token = 'x7dk55LtV0n1H4zbZEEazwbLxzH4WvqOjtTyEH+2zr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}