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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9f80a7bcd1c4749fbd5341ca0afcaf2a5439e3eb911d837f30cfc74977d47e' 
  AND token = 'jP0MU1F+BjpRamdOMhTxG8UgrfeMYOOmIpkB94v5W1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}