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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deff61b4ab119185ec5d2463e3d2f4fa464d7af14d3bddbe7bcaaac4ab896336' 
  AND token = 'gB6GMkZBSzhkJqGMCn3Nx84Oprn1dn4SDKm7rIDqfX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}