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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb66f2cb18b46f05e0cbd559fde13848afd907f0358b5c463aaa2170b82937c4' 
  AND token = 'Ppo4R1iRXoG7c5eUyDdOZLOsCFw6uiMoGR9zJdntbkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}