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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad9b4b582990e3231dca869d8941a4b735408f8768e9f5be84470ab539e29e0' 
  AND token = '3yi9YG1Re8SeLa7q7tLGWMw396G3bBcDMItRq4VQ6KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}