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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd76b66e12d32d2653ab058a1aa0188f16479fd85793dd106cc74170a40ab4d20' 
  AND token = 'XppEvBRG2EoEnSeKouPsL6wIAm/3sQ09CeKFtXGu1K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}