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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78224cf971042f2d40686182ca7407df7c0b12906ee3e8c177ccb22721d782f0' 
  AND token = 'xRVte5GdXek8oRla64w1EQVTjWY2daE8aKokGGSwXVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}