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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22d03f979a199dcc89dbb7f9b91adc530d0fe24a10267d117af4ee554b14bc6' 
  AND token = 'hzjCpSlaMBczyUrJ8n0vaxEqTrOn7Xe7NGRMedVltjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}