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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584d2e43321f70f43d7bf15bd9e1e1a9ad747ad296c4d7077be15b07f8c2a84f' 
  AND token = 'EYAYHxsJV9bXhRw4i5bNPLPy9NG2Ztg7u4p76lUdeDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}