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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f3a35759ec7261cd68feed39aa7905f183478dd6dd487d8f0d3bc9aef38d44' 
  AND token = '693nB2p0UaKO04DuNX46HPqtZ1fHm1s9liaQZBxKU/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}